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There are currently ten disorders for which there is an unequivocal recommendation against breeding in all breeds. These diagnoses are ineligible for OFA Eye Registry certifications.
These are conditions which frequently result in blindness and for which there is definite evidence of heritability in one or more breeds.
*Note: The prudent approach of these disorders is to assume they are hereditary except in cases specifically known to be associated with trauma, other causes of ocular inflammation, specific metabolic diseases or nutritional deficiencies.
Two categories of advice regarding breeding have been established by the Genetics Committee of the ACVO:
NO: Substantial evidence exists to support the heritability of this entity AND/OR the entity represents a potential compromise of vision or other ocular function. Refer to the section titled “Conditions that prevent eligibility for an OFA Eye Certification Number” for a list of disorders with an unequivocal recommendation against breeding, regardless of breed. Click here to see a complete listing of conditions which may make the dog ineligible for a certification number. Some of these conditions are breed specific.
BREEDER OPTION: Entity is suspected to be inherited but does not represent potential compromise of vision or other ocular function. Please note, although the dog will ‘pass’ it will have additional documentation on its OFA Eye Certification number with a category listing the problem. Click here to see a listing of Breeder Option Codes. Some Breeder Option Codes are breed specific.
When the breeding advice is ”NO,” even a minor clinical form of the entity would make this animal unsuitable for breeding. When the advice is ”BREEDER OPTION,” caution is advised. In time, it may be appropriate to modify this stand to “NO” based on accumulated evidence. If it becomes apparent that there is insufficient evidence that an entity is inherited, it may be deleted from the list.
Portions of the material above have been reprinted with permission of the American College of Veterinary Ophthalmologists from the publication “Ocular Conditions Presumed to be Inherited in Purebred Dogs”, 5th Edition, 2010, produced by the Genetics Committee of the American College of Veterinary Ophthalmologists, © American College of Veterinary Ophthalmologists.